Active Pharmaceutical Ingredients, (API), crystalline (6S)-5-Methyl-tetrahydrofolic Acid is used as a food supplement for folate deficiency and also in cases of depression disorders or as alternative of the Calcium Salt.
(6S)-5-Methyl-tetrahydrofolic Acid is the isomerically pure form of 5-Methyl-tetrahydrofolic Acid. In analogy with the corresponding Calcium sal, it can be used as nutritional supplement in case of folate deficiency, but also for treating some types of depressive disorders.
(6S)-5-Methyl-tetrahydrofolic Acid can be used as nutritional supplement in cases of folate deficiency which typically occur in a range of different situations like inadequate nutrition, absorption or utilization or increased requirements (pregnancy, lactation, malignancy) and whose possible consequences can be: birth defects (i.e. “spina bifida”), megaloblasticanemia, some types of depression.
For the use of (6S)-5-Methyl-tetrahydrofolic Acid in the nutritional field see Reduced Folates chapter.