Sodium Folinate

Chemical division

Formula

CERBIOS - PHARMA SA
CAS number: 42476-21-1

 

Synonyms

(6RS)-N5-Formyl-5,6,7,8-tetrahydrofolic Acid Sodium Salt
Disodium Folinate

 

Background and use

Concentrated and calcium free solutions of Sodium Folinate are suitable to be administered with 5-Fluorouracil solutions in the cancer therapy. For more information refer to the product sheets of Calcium Folinate and Folinic Acid and to the general Reduced Folates chapter

 

    • Active Pharmaceutical Ingredients (API)
    • Drug
      Substance
    • Patent
    • DMF
    • CEP
    • Sodium Folinate
    • •
    • •
    • •

 

Regulatory compliance

A DMF is available.

Intellectual property

  • Method of production of the precursor (6RS)-Calcium Folinate is patent protected
  • Formulated solutions of (6RS)-Sodium Folinate are patent protected (EP 667 159 ; US 5 814 635)

Packaging information

The active ingredient is packed in a low density polyethylene bag in a high density polyethylene aluminium bag in high density polyethylene containers up to 64 liters. Variable quantities of API up to 20kg of material per container are available.